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KMID : 0882419930440040446
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Korean Journal of Medicine
1993 Volume.44 No. 4 p.446 ~ p.453
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Comparison of the Effect of Hexabrix and Urografin 76 on Q-T Interval and ST-T wave of ECG during Coronary Angiography
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김용준
최은수/김승용/이상민/김용태/이홍순/유수웅/이학중
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Abstract
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ackground : Complications such as bradycardia, changes of T wave R-R interval, QRS
comples and S-T segment, premature atrial contracutre, premature vetricular contracture
ventricular tachycardia on ECG during coronary angiography may happedn. The are somwhat
caused by osmolarity, ionic concentration of Na+ and H+, molecular weight of contrast dye
and the change of coronary artery pressure during cornary angiography.
Methods ; We compared the changes of Q-Tc interval, S-T segment and T wave during
coronary angiography between high somolar (Urografin 76) and low osmolar contrast dye
(Hexabrix). The 32 patients with chest pain were studied and ECG was checked before and
1,2,5 minute after left and right coronary angiography.
Results ;
1) There was no significant difference in chage of S-T wave between the two groups
during left coronary angiography. And there was also no significant difference in change of
S-T wave during right coronary angiography.
2) The maximal prolongation of Q-Tc interval during left coronary angiography was 6.8
seconds in high osmolar group and 6.0 seconds in low osmolar group. The maximal
prologation of Q-Tc interval during right coronary angiography was 7.7 seconds in high
osmolar group and 6.3 seconds in low osmolar group.
3) There was significant prolongationof Q-Tc interval in high osmolar group (0.078±0.042
seonds) than that of low osmolar group (0.053±0.028 seconds) during left coronary
angiography (p<0.01). But the change of Q-Tc interval during right coronary angiography
was not significantly different.
Conclustions ; The prolongation of Q-Tc interval was more increased in high osmolar
contrast media group than in low osmolar. So the low osmolar contrast media was safer
than high osmolar contrast media and it need close observation espeically 6-8 seconds after
injection of contrast meida to prevent arrthythmia and other complications.
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KEYWORD
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